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      <p style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;text-align:center;" class=""><strong>Support the Global Fund's Eighth Replenishment</strong></p>
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  <a href="https://www.stoptbcanada.com/global-fund" style="color:#e7142c !important;"><img class="section-scaleable-image" src="https://images.squarespace-cdn.com/content/5e987dbef86c604f13d6555d/41e726aa-4d92-4062-afd9-ff906d01e99c/Global+Fund+Campaign.png?content-type=image%2Fpng&amp;format=750w" width="594" alt="" style="font-size:.7970742685671418em;display:block;border:0;text-decoration:none;line-height:0;background-color:transparent;font-weight:normal;height:auto;width:100%;max-width:100%;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"></a>


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      <p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;"><a href="https://www.theglobalfund.org/en/investment-case/" rel="nofollow" style="color:#e7142c !important;">The Global Fund to Fight AIDS, Tuberculosis and Malaria</a> is the world’s largest multilateral funder of TB programs, responsible for 76% of all international TB financing. </p><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;">Ahead of the Global Fund’s Eighth Replenishment this year, Stop TB Canada and partners are calling on the Government of Canada to continue its leadership in global health by making a strong and ambitious pledge. A fully funded Global Fund could save 23 million lives, prevent 400 million infections, and bring us closer to the goal of ending TB by 2030.</p><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;">TB remains the world’s leading infectious disease, but Canada, with a long history of championing global health, can play a vital role in ending it. Now is the time to recommit and #WinTheFight against the world’s deadliest epidemics.</p><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;"><a href="https://www.stoptbcanada.com/global-fund" rel="nofollow" style="color:#e7142c !important;"><strong>Learn more about the campaign.</strong></a></p><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;"><strong>Amplify our campaign by sharing the message below on social media:</strong></p><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;"><a href="https://ctt.ac/UbcQt" rel="nofollow" style="color:#e7142c !important;">HIV, TB &amp; malaria are the world's deadliest epidemics❗️Canada must help #WinTheFight against these preventable diseases by supporting the @GlobalFund to #Save23MillionLives. @MarkJCarney @RandeepSSarai @CanadaDev</a></p>
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      <p style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;text-align:center;" class=""><strong>Health Canada reviewing rifapentine drug submission</strong></p>
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  <a href="https://www.canada.ca/en/health-canada/services/drug-health-product-review-approval/submissions-under-review/new-drug-submissions-under-review.html" style="color:#e7142c !important;"><img class="section-scaleable-image" src="https://images.squarespace-cdn.com/content/5e987dbef86c604f13d6555d/9ece2d51-d133-40a4-9932-82158b643996/185226-macleod.jpg?content-type=image%2Fjpeg&amp;format=750w" width="594" alt="" style="font-size:.7970742685671418em;display:block;border:0;text-decoration:none;line-height:0;background-color:transparent;font-weight:normal;height:auto;width:100%;max-width:100%;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"></a>


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<table role="presentation" width="100%" cellpadding="0" cellspacing="0" border="0" bgcolor="transparent" class="text-section section-content">
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      <p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;">Health Canada is now reviewing a New Drug Submission (NDS) for rifapentine 150 mg tablets, a key medicine for shorter TB preventive treatment. Sponsored by Macleods Pharmaceuticals, the filing was accepted in March 2025 and follows extensive collaboration between Health Canada, the Public Health Agency of Canada, Unitaid, Indigenous Services Canada, and other partners. A decision is expected within the standard 300-day review period, pending any data gaps.</p><p style="color:inherit;font-size:1.0625em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;line-height:1.2;margin-top:0pt;margin-bottom:0pt;" class=""><strong>Learn more:</strong></p><ul data-rte-list="default" style="padding-left:25px;"><li style="font-weight:normal;margin-top:0px;margin-bottom:0px;margin-left:15px;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;"><a href="https://www.canada.ca/en/health-canada/services/drug-health-product-review-approval/submissions-under-review/new-drug-submissions-under-review.html" title="https://www.canada.ca/en/health-canada/services/drug-health-product-review-approval/submissions-under-review/new-drug-submissions-under-review.html" target="_blank" rel="nofollow noopener noreferrer" style="color:#e7142c !important;">Health Canada Submissions Under Review (SUR) list</a></p></li><li style="font-weight:normal;margin-top:0px;margin-bottom:0px;margin-left:15px;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p class="" style="color:inherit;font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;"><a href="https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/applications-submissions/guidance-documents/management-drug-submissions/industry/document.html" title="https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/applications-submissions/guidance-documents/management-drug-submissions/industry/document.html" target="_blank" rel="nofollow noopener noreferrer" style="color:#e7142c !important;">Health Canada Guidance: The Management of Drug Submissions and Applications</a></p></li></ul>
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  <a href="https://www.treatmentactiongroup.org/publication/south-africas-tb-and-hiv-research-at-risk/?eId=4c7dece0-bbf0-4394-9171-76646f1f6a78&amp;eType=EmailBlastContent" style="color:#e7142c !important;"><img class="section-scaleable-image" src="https://images.squarespace-cdn.com/content/5e987dbef86c604f13d6555d/51b68443-c41c-443a-bf53-4de04148bd31/TAG-.png?content-type=image%2Fpng&amp;format=750w" width="198" alt="" style="font-size:.7970742685671418em;display:block;border:0;text-decoration:none;line-height:0;background-color:transparent;font-weight:normal;height:auto;width:100%;max-width:100%;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"></a>


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      <div class="section-caption-text" style="position:relative;"><p class="" style="font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;"><a href="https://www.treatmentactiongroup.org/publication/south-africas-tb-and-hiv-research-at-risk/?eId=4c7dece0-bbf0-4394-9171-76646f1f6a78&amp;eType=EmailBlastContent" rel="nofollow" style="color:#e7142c !important;"><strong>South Africa’s TB and HIV Research at Risk: A Call to Catalyze Urgent Action by Funders</strong></a></p><p style="font-size:1.0625em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;line-height:1.4;margin-top:0px;margin-bottom:20px;" class="">Developed by TAG, Médecins Sans Frontières, and the South African Medical Research Council, this issue brief provides information about TB and HIV clinical trials and research programs impacted by U.S. government funding disruptions, and proposes urgent actions that donor agencies, governments, and philanthropies can take to preserve scientific advances underway and prevent the collapse of TB and HIV medical research in South Africa. <a href="https://www.treatmentactiongroup.org/publication/south-africas-tb-and-hiv-research-at-risk/?eId=4c7dece0-bbf0-4394-9171-76646f1f6a78&amp;eType=EmailBlastContent" rel="nofollow" style="color:#e7142c !important;">Learn more.</a></p></div>
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  <a href="https://www.msf.org/report-deadly-gaps" style="color:#e7142c !important;"><img class="section-scaleable-image" src="https://images.squarespace-cdn.com/content/5e987dbef86c604f13d6555d/ee38dc56-01c9-46de-8e52-def0b1b5dc2d/Screenshot+2025-05-29+095427.png?content-type=image%2Fpng&amp;format=750w" width="198" alt="" style="font-size:.7970742685671418em;display:block;border:0;text-decoration:none;line-height:0;background-color:transparent;font-weight:normal;height:auto;width:100%;max-width:100%;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"></a>


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      <div class="section-caption-text" style="position:relative;"><p style="font-size:1.0625em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;line-height:1.5625rem;margin-top:1.7em;margin-bottom:1.25rem;" class=""><a href="https://www.msf.org/report-deadly-gaps" rel="nofollow" style="color:#e7142c !important;"><strong>Deadly Gaps: Don't turn away from saving lives</strong></a></p><p style="font-size:1.0625em;margin:0 0 1.25em 0;font-weight:normal;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;line-height:1.5625rem;margin-top:1.7em;margin-bottom:1.25rem;" class="">Ahead of the upcoming Global Fund Replenishment Conference, Médecins Sans Frontières (MSF) has released a report based on its experience with the communities it serve, highlighting the challenges this replenishment faces, including the impact of shrinking donor support. <a href="https://www.msf.org/report-deadly-gaps" rel="nofollow" style="color:#e7142c !important;">Learn more.</a> </p></div>
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  <a href="https://www.treatmentactiongroup.org/publication/magic-mountains-of-debt-sovereign-debt-crises-as-critical-barriers-to-ending-tb-and-investing-in-sustainable-development-goals/?eId=618c5319-eabf-43d6-af1c-65ea0996785f&amp;eType=EmailBlastContent" style="color:#e7142c !important;"><img class="section-scaleable-image" src="https://images.squarespace-cdn.com/content/5e987dbef86c604f13d6555d/39fcf917-367e-41c6-9f18-59ff84ceeab9/TAG-.png?content-type=image%2Fpng&amp;format=750w" width="198" alt="" style="font-size:.7970742685671418em;display:block;border:0;text-decoration:none;line-height:0;background-color:transparent;font-weight:normal;height:auto;width:100%;max-width:100%;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"></a>


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      <div class="section-caption-text" style="position:relative;"><p class="" style="font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;"><a href="https://www.treatmentactiongroup.org/publication/magic-mountains-of-debt-sovereign-debt-crises-as-critical-barriers-to-ending-tb-and-investing-in-sustainable-development-goals/?eId=618c5319-eabf-43d6-af1c-65ea0996785f&amp;eType=EmailBlastContent" rel="nofollow" style="color:#e7142c !important;"><strong><span style="font-size:inherit;font-weight:inherit;line-height:inherit;margin:0;text-decoration:underline;">Magic Mountains of Debt: Sovereign Debt Crises as Critical Barriers to Ending TB and Investing in Sustainable Development Goals</span></strong></a></p><p class="" style="font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;">The global debt crisis threatens investment in TB programs and research and progress towards Sustainable Development Goals at large. This issue brief analyzes the impact  of sovereign debt in depressing investments in TB programs, services, and R&amp;D in high-TB burden nations. It also makes the case for novel approaches to addressing the debt crisis now and in the future. <a href="https://www.treatmentactiongroup.org/publication/magic-mountains-of-debt-sovereign-debt-crises-as-critical-barriers-to-ending-tb-and-investing-in-sustainable-development-goals/?eId=618c5319-eabf-43d6-af1c-65ea0996785f&amp;eType=EmailBlastContent" rel="nofollow" style="color:#e7142c !important;">Learn more.</a></p></div>
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  <a href="https://www.sciencedirect.com/science/article/abs/pii/S0140673625008049?dgcid=coauthor" style="color:#e7142c !important;"><img class="section-scaleable-image" src="https://images.squarespace-cdn.com/content/5e987dbef86c604f13d6555d/81221aaf-2166-4395-88d7-06ad7d6790b6/OIP.jpg?content-type=image%2Fjpeg&amp;format=750w" width="198" alt="" style="font-size:.7970742685671418em;display:block;border:0;text-decoration:none;line-height:0;background-color:transparent;font-weight:normal;height:auto;width:100%;max-width:100%;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;"></a>


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      <div class="section-caption-text" style="position:relative;"><p class="" style="font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-top:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;"><a href="https://www.sciencedirect.com/science/article/abs/pii/S0140673625008049?dgcid=coauthor" rel="nofollow" style="color:#e7142c !important;"><strong>Moving the dial on diagnostics: an update from the Lancet Commission on diagnostics</strong></a></p><p class="" style="font-size:1.0625em;line-height:1.618em;margin:0 0 1.25em 0;font-weight:normal;margin-bottom:0;font-family:'DejaVu Sans Condensed', 'Liberation Sans', 'Nimbus Sans L', 'Helvetica Neue', Helvetica, Arial, sans-serif;letter-spacing:-.01em;color:#313131;">A new Lancet publication reviews global progress on ten key recommendations for improving diagnostic access and equity. While political will and policy alignment have driven gains in several areas, challenges remain - especially in affordability, workforce, and access in conflict settings. <a href="https://www.sciencedirect.com/science/article/abs/pii/S0140673625008049?dgcid=coauthor" rel="nofollow" style="color:#e7142c !important;">Learn more.</a></p></div>
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